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Many insects left "oviposition markers" on the surface of the eggs or at the egg-laying site after oviposition. It was found that "oviposition markers" were chemical-oviposition deterrents (OVD) produced by female adults,which deterred oviposition at the same sites by conspecific or heterospecific females. It was confirmed that the larvae of many insects could secret OVD. The species in Orthoptera,Lepidoptera,Coleoptera and Diptera could also produce OVD. Many documents confirmed that there were chemicals functioning as OVD in many kinds of plants. A set of techniques for studying OVD such as electrophysiological responses,behavioral responses,and isolation and identification of active compounds has now been developed. The OVD produced by females of Pieris rape,Lasioderma serricorne and Rhagoletis cerasi were identified and synthesized. The chemicals functioning as OVD of Pieris rape and Hylemya spp. were found in many plants. Controlling Rhagoleris cerasi with OVD was a typical example in the application of OVD. In addition,a new variety of cotton that could deter oviposition by females of Anthonomus grandis was also developed. OVD could also be used to study coevolutionary relationship between herbivore insects and plants. We think that study on OVD of insects plays a very important role in decoding the ovipositional behaviors of insects,co-evoluationary relationship between herbiore insects and plants,and developing new types of pest insect-controlling techniques.