Cancer antigen-specific cytotoxic T lymphocytes (CTL) are the major effectors against cancer cells.However, large established tumors are usually not fully c
Surgery has practically, only cured a small proportion of some localised solid tumors.Radiotherapy, given as complement of conservative surgery, increased i
Human leukocyte antigen-G (HLA-G) is a non-classical HLA class Ib molecule of low polymorphism whose expression is restricted to immunoprivileged sites, suc
Incidence of brain metastasis has been increasing in the recent years, however, its molecular mechanism is poorly understood to date.In cancer metastasis, i
Perforin (PRF) is a member of the MACPF (membrane-attack-complex-perforin) domain protein family, which we have recently discovered have the same molecular