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血浆内皮素(Endothelin,ET)是由21个氨基酸组成的多肽,首先由Yangisawa以猪的主动脉内皮细胞的培养液中分离提取得到的缩血管物质,以后在人的内皮细胞和血液中也发现了该物质,目前已知有三种内皮素,分别叫做ET-1,ET- 2和ET-3,对心血管系统可能有重要的生理和病理的意义的是ET-1,它是迄今为止最为强烈的缩血管物质,使用放射免疫法可直接测定血浆ET浓度.本文对141例患者进行了血浆ET含量测定,并作初步分析和探讨.材料和方法一、正常对照组:20例健康体检人民,其中男、女各10例,年龄14～65岁.二、疾病组:141例均(男89例,女52例)为我院住院病人,年龄20～84岁,疾病诊断参考临床诊断和各项物理检查结果综合作出.
Endothelin (ET) is a polypeptide consisting of 21 amino acids. First, the vasoconstrictor substance was isolated from the culture fluid of porcine aortic endothelial cells by Yangisawa, and later found in human endothelial cells and blood The substance, now known as ET-1, ET-2 and ET-3, is known to have an important physiological and pathological significance for the cardiovascular system and is by far the most potent Strong vasoconstrictor substances, the use of radioimmunoassay method can be directly measured plasma ET concentration.In this paper, 141 patients were measured by plasma ET levels, and for the initial analysis and discussion.Materials and Methods A normal control group: 20 healthy people , Of which 10 males and 10 females, aged 14 to 65. Second, the disease group: 141 cases (89 males and 52 females) for our hospitalized patients, aged 20 to 84 years old, the diagnosis of disease refers to the clinical diagnosis and The physical examination results made.