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目的观察氟比洛芬酯(凯纷)超前镇痛用于无痛人工流产术后镇痛效果和不良反应的发生情况。方法 ASAⅠ～Ⅱ级行无痛人工流产术的孕妇200例,随机分为A、B2组,每组100例。A组预先给予凯纷,B组给予安慰剂(脂肪乳),2组再分别给予芬太尼与丙泊酚,观察麻醉诱导前、意识消失时、扩宫结束时、苏醒时的HR、MAP、SpO2,记录丙泊酚用量、苏醒时间、不良反应、术后5min及30min宫缩痛情况。结果在意识消失时及扩宫结束时,A组MAP水平明显高于B组(P<0.05),即降低幅度较小;丙泊酚用量A组少于B组(P<0.05);体动发生率A组明显低于B组(P<0.05);2组患者苏醒30min时,宫缩痛发生率A组明显低于B组(P<0.01)。结论氟比洛芬酯超前镇痛用于无痛人工流产术可增强麻醉效果,减少丙泊酚用量,可明显减少术后宫缩痛。
Objective To observe the analgesic effects and side effects of flurbiprofen axetil (Triptych) advanced analgesia for painless induced abortion. Methods Two hundred and seventy pregnant women with ASA Ⅰ ~ Ⅱ painless induced abortion were randomly divided into groups A and B2, with 100 in each group. Group A was given Kefir in advance, Group B was given placebo (fat emulsion), and then two groups were given fentanyl and propofol respectively. Before anesthesia induction, consciousness disappeared, at the end of dilation, resuscitation HR, MAP , SpO2, record the amount of propofol, recovery time, adverse reactions, 5min and 30min after uterine contractions. Results At the disappearance of consciousness and at the end of dilation, the level of MAP in group A was significantly higher than that in group B (P <0.05), that is, the decrease was smaller; the dosage of propofol in group A was less than that in group B (P <0.05) The incidence of group A was significantly lower than that of group B (P <0.05). The incidence of uterine contractions in group A was significantly lower than that in group B (P <0.01) after 30 minutes of recovery. Conclusion The application of flurbiprofen axetil analgesia in painless artificial abortion can enhance the anesthetic effect, reduce the dosage of propofol, and reduce the postoperative contractions pain obviously.