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目的:探讨曲安奈德玻璃体腔注射联合血塞通治疗急性视神经炎的疗效。方法:将82例急性视神经炎患者(90眼),随机分为治疗组41例(46眼)和对照组41例(44眼),治疗组予曲安奈德联合血塞通治疗,对照组予常规治疗,比较两组疗效。结果:治疗组总有效率为97.8%,对照组为88.6%,差异有统计学意义(P<0.05);治疗组治疗后视盘颜色正常比例为93.5%,对照组为88.6%,两组比较,差异无统计学意义(P>0.05);治疗组治疗后眼压高峰明显提前,治疗组平均眼压值为(17.45±4.22)mm Hg,对照组平均眼压值为(17.15±5.03)mm Hg,两组眼压值比较,差异无统计学意义(P>0.05);两组并发症比较,差异无统计学意义(P>0.05)。结论:曲安奈德玻璃体腔注射联合血塞通注射液治疗急性视神经炎安全有效。
Objective: To investigate the efficacy of triamcinolone acetonide vitreous cavity injection combined with Xuesaitong in the treatment of acute optic neuritis. Methods: A total of 82 patients with acute optic neuritis (90 eyes) were randomly divided into treatment group (n = 41) (41 eyes) and control group (n = 41). The treatment group was treated with triamcinolone acetonide combined with Xuesaitong, Routine treatment, the two groups were compared. Results: The total effective rate was 97.8% in the treatment group and 88.6% in the control group, with a significant difference (P <0.05). The normal color of the optic disc in the treatment group was 93.5% and the control group was 88.6% The intraocular pressure (IOP) of the treatment group was significantly higher than that of the control group (17.45 ± 4.22) mm Hg, and the mean IOP of the control group was (17.15 ± 5.03) mm Hg There was no significant difference in intraocular pressure between the two groups (P> 0.05). There was no significant difference in complication between the two groups (P> 0.05). Conclusion: Triamcinolone acetonide vitreous cavity injection combined with Xuesaitong injection in the treatment of acute optic neuritis is safe and effective.