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以 3 硝基水杨酸和正癸烷为原料 ,合成了研究线粒体呼吸链酶系中各泛醌结合蛋白的分子探针 ,即氚标记的 3 叠氮基 N 正癸烷基水杨酰胺 ,为进一步研究泛醌结合蛋白提供了有效工具。3 H 3 叠氮基 N 正癸烷基水杨酰胺的放射性比活度和放射化学纯度分别为 2 5 9TBq/mol和 98%
Using 3-nitrosalicylic acid and n-decane as raw materials, a molecular probe to study the ubiquinone binding proteins in mitochondrial respiratory chain enzymes was synthesized. The tritiated 3-azido N-n-decyl salicylamide was Further study of ubiquinone binding protein provides an effective tool. The radioactivity and radiochemical purity of 3 H 3 azido N-n-decyl salicylamide were 259 TBq / mol and 98%