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反义核酸是指与体内某RNA或DNA序列具有互补顺序,并能通过碱基配对与互补链杂交,从而影响其转录或翻译过程的RNA或DNA片段。反义RNA和DNA的特异性源自反义序列和靶序列之间的碱基配对。反义核酸的长度可长可短,长的反义核酸一般都借助表达载体导入细胞,
An antisense nucleic acid refers to an RNA or DNA fragment that has a complementary sequence to an RNA or DNA sequence in the body and can hybridize with the complementary strand by base pairing to affect its transcription or translation process. The specificity of antisense RNA and DNA results from base pairing between the antisense sequence and the target sequence. Antisense nucleic acids can be long or short, long antisense nucleic acids are generally introduced into cells by means of expression vectors,