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目的观察连续性肾替代治疗(CRRT)治疗肾功能衰竭伴多脏器功能障碍(MODS)患者的疗效。方法将26例肾功能衰竭伴MODS患者随机分成治疗组及对照组。治疗组10例,除常规治疗外加用CRRT治疗;对照组16例,采取常规治疗。观察治疗前、后血二氧化碳结合力、尿素氮、肌酐、血钾、血钠、血氯等的变化。比较两组的疗效及死亡率。结果与对照组比较,CRRT治疗组肾功能和血生化指标维持稳定(P<0.05)。CRRT治疗组患者存活、肾功能恢复率和死亡率情况明显优于对照组。结论 CRRT治疗肾功能衰竭伴MODS的疗效明显优于常规治疗,提高了患者的救治成功率。
Objective To observe the effect of continuous renal replacement therapy (CRRT) on patients with renal failure and multiple organ dysfunction (MODS). Methods Twenty-six patients with renal failure and MODS were randomly divided into treatment group and control group. The treatment group of 10 cases, in addition to conventional treatment plus CRRT treatment; control group of 16 patients, to take routine treatment. Changes of blood carbon dioxide, urea nitrogen, creatinine, serum potassium, serum sodium and blood chlorine before and after treatment were observed. Efficacy and mortality were compared between the two groups. Results Compared with the control group, the renal function and blood biochemical parameters remained stable in the CRRT treatment group (P <0.05). CRRT treatment group survival, renal function recovery and mortality was significantly better than the control group. Conclusion CRRT treatment of renal failure with MODS was significantly better than conventional treatment, improve the success rate of treatment of patients.