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运用巢式聚合酶链反应（nested－PCR）检测36例经外科手术治疗的肝细胞癌（HCC）患者的肝癌组织或癌周组织中的丙型肝炎病毒（HCV）RNA，并检测血清中的乙型肝炎病毒（HBV）表面抗原来显示HCC患者中HCV和HBV的感染情况，同时收集一般临床资料。结果表明36例HCC患者中，HCV感染者13例（36．1％）．HBV感染者30例（83．3％），两者重叠感染者12例（33．3％），并发现HCV、HBV重叠感染者较仅HBV感染者肝癌直径较大，血清ALT平均值较高，术后1年生存率较差；而在发病年龄，血清AKP、AFP阳性率等方面均无差别，提示HCV、HBV重叠感染可加速肝癌发展，手术预后较差。
Nested-PCR was used to detect hepatitis C virus (HCV) RNA in liver cancer tissue or pericancerous tissue in 36 surgically treated hepatocellular carcinoma (HCC) patients and to detect serum Hepatitis B virus (HBV) surface antigens are used to display HCV and HBV infection in HCC patients, and general clinical data are collected. The results showed that among 36 patients with HCC, 13 cases (36.1%) were infected with HCV. There were 30 cases (83.3%) with HBV infection and 12 cases (33.3%) with overlapping infections. HCV and HBV overlap infections were found to have larger diameters of liver cancer than those with HBV infection, and the mean serum ALT was higher. The 1-year postoperative survival rate was poor, but there was no difference in serum AKP and AFP positive rates at the age of onset, suggesting that HCV and HBV overlap infection could accelerate the development of liver cancer and the prognosis of the surgery was poor.