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目的 解决国内在缺乏昂贵ＮＯ浓度监测仪的情况下应用一氧化氮吸入疗法技术的难题。方法 １７只犬随机分为二组，吸入性损伤模型成功后，对照组单纯吸氧（ＦｉＯ２，０．４５），治疗组吸氧（ＦｉＯ２，０．４５）＋０．００４５％（４５ｐｐｍ）ＮＯ。ＮＯ输送系统由三个转子流量计分别控制 Ｏ２，Ｎ２和 ＮＯ三种气体管道出口，按需调节三股气体流量比例，在呼吸回路的吸入支置钠石灰罐。 ＦｉＯ２和二氧化氮（（ＮＯ２）数据行多个样本均间方差分析，ＮＯ行两样本均数间ｔ检验。结果ＦｉＯ２实测值比预计值高１０．８％（Ｐ＞０．０５），ＮＯ２在钻石灰处理后比钠石灰处理前降低８０．２％（Ｐ＜０．０１），ＮＯ实测值比预计值高１１％（Ｐ＞０．０５）。结论 本系统既避免了产生过高ＮＯ２的危险，同时又克服了ＮＯ浓度不恒定的缺点，能较好地满足基础实验研究。
Objective To solve the problem of using nitric oxide inhalation therapy technology in the absence of expensive NO concentration monitor in China. Methods Seventeen dogs were randomly divided into two groups. After successful inhalation injury model, the control group received FiO2 (0.45), FiO2 (0.45) + 0.0045% (45ppm) NO. NO transport system consists of three rotor flowmeter were controlled O2, N2 and NO three gas pipeline outlets, according to the need to regulate the proportion of three gas flow, inhalation of breathing circuit support soda lime pot. FiO2 and NO2 data were analyzed by means of ANOVA, and NO was used to test the t test between two samples.Results The measured value of FiO2 was 10.8% higher than expected (P> 0.05), NO2 (P <0.01), and NO was 11% higher than the predicted value (P> 0.05) .Conclusion The system not only avoids the excessive production of NO2 The danger of overcoming the NO concentration is not constant shortcomings, can better meet the basic experimental research.