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目的进一步了解单纯疱疹病毒性脑炎病人的脑脊液细胞学特点及其应用价值。方法３０例病例均经免疫学（ＨＳＶ抗原检查和ＰＣＲ）和临床确诊，采用常规的脑脊液细胞玻片离心沉淀法收集细胞，经ＭＧＧ染色后在显微镜油镜下进行逐个细胞检查。结果仅１４例病例（４６６％）的常规脑脊液白细胞计数有增高，而脑脊液细胞学检查全部病例均有异常，且以淋巴细胞比例升高为主的淋巴细胞反应为多见（６６７％）。结论单纯疱疹病毒性脑炎的常规脑脊液细胞学检查的异常率高于常规脑脊液白细胞计数检查，且符合以淋巴细胞比例升高为主的一般病毒性脑炎的脑脊液细胞学异常规律。故具有一定的临床诊断和鉴别诊断价值。脑脊液细胞计数的高低和脑脊液细胞学异常的类型似与ＨＳＶ类型无关
Objective To further understand the cerebrospinal fluid cytology and its application in patients with herpes simplex virus encephalitis. Methods Thirty patients were diagnosed by immunology (HSV antigen test and PCR) and clinically diagnosed. Cells were collected by routine cerebrospinal fluid cell suspension centrifugation and stained with MGG for cell-by-cell microscopic examination. Results In only 14 cases (466%), the routine cerebrospinal fluid leucocyte count was increased. However, all the cases of CSF abnormalities were abnormal, and the lymphocyte reaction with lymphocyte proportion increased was more common (667 %). Conclusions The abnormal rate of routine cerebrospinal fluid cytology in herpes simplex virus encephalitis is higher than that of routine cerebrospinal fluid leukocyte count and accords with the abnormal cerebrospinal fluid cytology of general viral encephalitis with the increase of lymphocyte proportion. It has a certain clinical diagnosis and differential diagnosis. The level of cerebrospinal fluid cytometry and cerebrospinal fluid cytology abnormalities similar to the type of HSV has nothing to do