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抗生素是目前临床应用最广泛的药物之一。据文献报导,我国使用抗生素的住院病人比例在70％以上。随着新的抗生素不断地出现、细菌对抗生素敏感度及流行病学的不断变化、抗生素使用的方法日趋复杂、以及细菌的耐药性增强和药源性疾病的增多,使我们不得不对抗生素的临床合理应用更加重视。1 抗生素的合理使用原则1·1 严格掌握抗生素使用的适应症 首先必须熟悉所选用药物的抗菌谱、临床适应症、药物动力学特点(吸收、分布、
Antibiotics is currently one of the most widely used drugs in clinical practice. According to the literature, the proportion of inpatients using antibiotics in our country is over 70%. As new antibiotics continue to emerge, bacteria are constantly changing in their susceptibility and epidemiology of antibiotics, the use of antibiotics is becoming more complex, and bacterial resistance and drug-related illnesses increase, making us resistant to antibiotics Clinical application of more reasonable attention. 1 principles of rational use of antibiotics 1.1 strict control of indications for antibiotics First must be familiar with the antimicrobial spectrum of selected drugs, clinical indications, pharmacokinetic characteristics (absorption, distribution,