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随着人口老龄化和严重创伤疾病的增加,骨科内植物已成为重建人体骨关节结构和功能的重要外科治疗手段,有着巨大的临床需求和快速增长的市场份额。然而,由于我国在内植物研发水平上与发达国家之间的巨大差距,导致我国现今大部分市场份额被进口内植植物所占据。同时,植入物在临床应用中仍面临着在材料、设计和制造等方面进一步优化与提高的诸多挑战。如何针对国人的解剖生理特点及生活习性需求,在内植物设计与研发理念上有所创新与突破,提高“中国设计与制造”内植物的研发水平,是当前亟待解决的问题。为应对上述问题,于2009年启动建立了骨科失效内植物与组织标本库,它是国内首个集失效内植入物材料、植入物周围生物样本与组织标本、相关实验分析数据以及患者医疗信息为一体的骨科临床内植物库,将为研究和分析植入物失效原因、促进内植物的创新研发、为推动骨科转化医学研究提供重要临床支持和借鉴参考。
With the aging of the population and the increase of severe traumatic diseases, orthopedic implants have become an important surgical treatment for reconstructing the structure and function of the human bone and joint. They have great clinical needs and rapid growth in market share. However, due to the huge gap between our country and the developed countries in the research and development of endophytes, most of our market share is now occupied by imported plants. At the same time, implants still face many challenges in further optimization and improvement in materials, design and manufacture in clinical application. How to address the needs of Chinese people’s anatomical and physiological characteristics and habits, innovation and breakthroughs in the concept of plant design and research and development, improve the “China Design and Manufacturing ” plant research and development level, is the immediate problem to be solved. In response to the above-mentioned problems, a database of implants and tissues of implants was established in 2009, which is the first implants material in China that has failed to be implanted, biological samples and tissue samples around implants, relevant experimental data and patient medical Information as one of the Orthopedic Clinical Endocrinology Database will provide important clinical support and reference for the research and analysis of the causes of implants failure to promote the innovative research and development of implants.