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目的 :观察比较碳酸钙口服混悬液和硫糖铝口服混悬液治疗小儿功能性消化不良的临床疗效和安全性。方法 :采用多中心随机对照方法 ,将200例2岁～14岁患有功能性消化不良的患儿随机分成两组 ,分别给予碳酸钙口服混悬液 (以下简称治疗组 )和硫糖铝口服混悬液 (以下简称对照组 )治疗。结果 :治疗组患儿服药后第7天和第10天上腹痛缓解程度以及症状总改善率明显优于对照组 ;治疗组各种症状的缓解起效时间明显快于对照组 ;治疗组综合疗效和有效率明显高于对照组。结论 :碳酸钙口服混悬液对缓解小儿功能性消化不良症状的疗效明显优于硫糖铝口服混悬液 ,且起效更快。
Objective: To observe the clinical efficacy and safety of oral calcium carbonate oral suspension and sucralfate oral suspension in the treatment of functional dyspepsia in children. Methods: A total of 200 children with functional dyspepsia aged 2-14 years old were randomly divided into two groups by randomized controlled multicenter study. The patients were given oral suspension of calcium carbonate (hereinafter referred to as the treatment group) and sucralfate orally Suspension (hereinafter referred to as the control group) treatment. Results: On the 7th day and the 10th day after treatment, the relief rate of the upper abdominal pain and the total improvement rate of the symptoms in the treatment group were significantly better than those in the control group. The onset and the onset of various symptoms in the treatment group were significantly faster than those in the control group. The comprehensive efficacy and Effective rate was significantly higher than the control group. CONCLUSION: The effect of oral calcium carbonate oral suspension on alleviating pediatric functional dyspepsia is better than that of sucralfate oral suspension and its onset is faster.