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目的了解信阳地区主要传疟媒介中华按蚊药物敏感性状况,为制定防治策略提供依据。方法WHO推荐的成蚊滤纸接触筒法,用溴氰菊酯(0.05%)、DDT(4%)、马拉硫磷(5%)3种药纸对中华按蚊雌性成蚊进行测试。结果信阳9县区中华按蚊对溴氰菊酯、DDT、马拉硫磷的死亡率(或校正死亡率)范围分别为22.22%~100%、11.11%~100%、25.33%~100%;不同县区中华按蚊对同一杀虫剂的抗性级别均有从敏感群体(S)到抗性群体(R)的分布;9县区中华按蚊对溴氰菊酯、DDT的首只击倒时间范围为1.0~23.78min、0.5~53.67 min,60 min击倒率范围为3.92%~75%、3.96%~95.05%,KT50范围为42.02~1 459.54min、35.23~1 459.54 min。结论信阳地区9县区中华按蚊对3种杀虫剂敏感性不全相同,存在地域差异。
Objective To understand the drug susceptibility of Anopheles sinensis in Xinyang, China, and to provide basis for prevention and control strategies. Methods The mosquito filter paper contact tube method recommended by the WHO was used to test female adult mosquitoes of Anopheles sinensis using three kinds of drug films of deltamethrin (0.05%), DDT (4%) and malathion (5%). Results The mortality (or corrected mortality) of Anopheles sinensis in Xinyang 9 counties ranged from 22.22% to 100%, from 11.11% to 100% and from 25.33% to 100% for deltamethrin, DDT and malathion respectively. The resistance levels of Anopheles sinensis to the same insecticide in different counties were all from the sensitive group (S) to the resistant group (R); the first hit of the 9 counties Anopheles sinensis against deltamethrin and DDT The pouring time ranged from 1.0 to 23.78 min and from 0.5 to 53.67 min, respectively. The knockdown rates ranged from 3.92% to 75% and 3.96% to 95.05% at 60 min and ranged from 42.02 to 1459.54 min and 35.23 to 1459.54 min, respectively. Conclusion The sensitivity of Anopheles sinensis in 9 counties and districts of Xinyang to the three insecticides is not the same, and there are geographical differences.