氯化奎宁(Chlorquine)治疗风湿样关节炎并发剝脫性皮炎

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近年来应用杭瘧藥物治疗风湿样关节炎,已經获得一定的疗效。其中以氯化奎宁应用最广。其作用是累积性的,需数周方見效。一般剂量为每日250mg,至少要隔4~12周以后才能对此藥物的疗效作出适当評价。氯化奎宁的毒性低且是暫时性的,可以因停藥或繼续服用足量或減量的藥物而完全消退。附一例报告:女性患者,58岁,患有风湿样关节炎。自1957年10月2日开始,每日口服氯化奎宁250mg,20天后,患者的大腿及腋窩外有灼热感,并有厌食、寒战与发 In recent years, the application of anti-malarial drug treatment of rheumatoid arthritis, has obtained a certain effect. Among them, quinine chloride is the most widely used. Its role is cumulative, take a few weeks effective. The general dose of 250mg daily, at least every 4 to 12 weeks to make a proper evaluation of the efficacy of this drug. Toxicity of quinuclidine is low and temporary, and can be completely dissipated due to discontinuation or continued administration of sufficient or low doses of the drug. Attached a case report: female patient, 58 years old, suffering from rheumatoid arthritis. Since October 2, 1957, daily oral administration of 250ml of quinine chloride, 20 days later, the patient’s thighs and axillary heart burning, and anorexia, chills and hair
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