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通过对应用肾上腺糖皮质激素(简称激素)治疗后发生21例肺结核的分析,总结本组病例有以下特征:①临床症状多隐匿而不典型.而咯血痰常为诊断的主要线索;②以血行播散型肺结核、浸润型肺结核多见。前者易合并结核性脑膜炎及肾结核(分别有5例和2例),后者双肺均可见较为广泛的病灶(12例中有8例),易形成空洞(12例中有6例)。且两者都易出现肺部以外多部位的结核并发症;③痰涂片结核杆菌阳性率达100%;④白血病和系统性红斑狼疮(简称SLE)为基础原发病,发生肺结核前后,有多种合并症及并发症,病程长,抗结核治疗疗效差,本组死亡6例(6/12)。肺结核的发生与应用激素剂量大小、时间长短有关。此外,还讨论了本病的发病机制及有关的鉴别诊断。
Through the application of adrenal glucocorticoid (referred to as hormone) after treatment of 21 cases of tuberculosis analysis concluded that the group of patients have the following characteristics: ① clinical symptoms and more occult atypical. The hemoptysis sputum often diagnosed the main clues; ② hematogenous disseminated pulmonary tuberculosis, infiltrative pulmonary tuberculosis more common. The former was easily associated with tuberculous meningitis and renal tuberculosis (5 cases and 2 cases, respectively), while the latter cases showed more extensive lesions in both lungs (8 of 12 cases) and easily formed cavities (6 of 12 cases) . And both are prone to tuberculosis complications outside the lungs; sputum smear Mycobacterium tuberculosis positive rate of 100%; ④ leukemia and systemic lupus erythematosus (SLE) based on the primary disease, before and after the occurrence of tuberculosis, there A variety of complications and complications, long duration, anti-TB treatment of poor efficacy in this group of 6 patients died (6/12). The occurrence and application of tuberculosis hormone dose size, the length of time. In addition, the pathogenesis of this disease and the related differential diagnosis are also discussed.