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活血化瘀法是急腹症的一个主要治法,广泛应用于阑尾炎、腹膜炎、胰腺炎及肠粘连等的治疗。活血化瘀汤是本所进行实验研究的代表方剂,已证实能增加犬肠血流,促进家兔腹腔吸收,增加纤溶,降低纤维蛋白原含量,减少家兔腹腔内粘连的发生等。由于肠血液动力学自动调节机制的存在,肠血流降低不一定减少肠组织氧耗,而血管扩张因子不一定增加氧耗,但是保持肠组织氧耗对保护肠组织又具有特别重要的意义。本实验设计着重探讨活血化瘀汤对犬小肠血流及氧耗等血液动力学的影响。
The method of promoting blood circulation and removing blood stasis is a major treatment for acute abdomen and is widely used in the treatment of appendicitis, peritonitis, pancreatitis and intestinal adhesions. Huoxue Huayu Decoction is the representative of the Institute for Experimental Research. It has been proved that it can increase intestinal blood flow in dogs, promote abdominal absorption in rabbits, increase fibrinolysis, reduce fibrinogen content, and reduce the incidence of intra-abdominal adhesions in rabbits. Due to the presence of autoregulatory mechanisms of intestinal hemodynamics, lower intestinal blood flow does not necessarily reduce the oxygen consumption of the intestine tissue, whereas the vasodilator factor does not necessarily increase oxygen consumption, but maintaining the oxygen consumption of the intestinal tissue is particularly important for the protection of intestinal tissue. This experiment was designed to focus on the effect of Huoxue Huayu Decoction on blood flow and oxygen consumption in the small intestine of dogs.