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病例病例31岁,男。主诉呼吸困难,浮肿。既往史1959年扁桃体切除术。家族史无特殊可记。现病史于5年前5月,发现两下肢浮肿,曾于某院就医,指出有大量蛋白尿。同年8月住院(第一次)确认有高度蛋白尿、低蛋白血症及高脂血症,诊断为肾病综合征,投与强的松。同年9月进行活组织检查(图1)。其后症状并无改善,由于对激素有抵抗作用加用硫唑嘌呤,但尿蛋白仍不见减少。第二
Case history 31 years old, male. Chief complaint of dyspnea, edema. Past history 1959 tonsillectomy. No special history of the family history. Current medical history in May 5 years ago, found two lower limb edema, had a hospital for medical treatment, pointed out that a large number of proteinuria. The same year in August hospitalization (for the first time) confirmed a high proteinuria, hypoproteinemia and hyperlipidemia, diagnosis of nephrotic syndrome, administration of prednisone. The same year in September for biopsy (Figure 1). Subsequent symptoms did not improve, due to hormone resistance plus azathioprine, but still no decrease in urinary protein. second