论文部分内容阅读
本文报告一例白血病前期(简称白前)小儿,以羟甲雄酮治疗显效后变为急性粒细胞白血病。患儿男性12岁,1974年8月7日以活动后气急、轻度跌打易见皮下出血而就诊。既往、家族史无特殊,贫血貌,皮下可见多处出血斑,肝脾阴性。血象:Hb5.5g%,RBC161万/mm~3,红细胞压积18%,高度大细胞正色性贫血,网织红细胞1.1%,血小板2.7万/mm~3,WBC 3200/mm~3,涂片见中性粒细胞减少,淋巴细胞百分率高,细胞形态无异常,红细胞中等大小不等,无幼稚细胞。骨髓有核细胞数及巨核细胞稍减少,淋巴比例增高,粒红比例正常。铁粒染色:铁粒幼细胞占82%,铁颗粒粗大,但未见环状铁粒幼细胞。尿便常规结果正常。
This article reports a case of pre-leukemia (referred to as pre-white) children, with oxymatrone treatment markedly become acute myeloid leukemia. Male 12-year-old children, August 7, 1974 after the event, shortness of breath, easy to see subcutaneous bleeding and treatment. Past, family history of no special, anemia appearance, multiple subcutaneous bleeding spots, liver and spleen negative. Blood: Hb5.5g%, RBC161 million / mm ~ 3, hematocrit 18%, high degree of large cell orthochromatic anemia, reticulocyte 1.1%, platelet 27000 / mm ~ 3, WBC 3200 / mm ~ 3, smear See neutropenia, high percentage of lymphocytes, no abnormal cell morphology, red blood cells ranging from medium size, naive cells. The number of bone marrow nucleated cells and megakaryocytes decreased slightly, the proportion of lymph nodes increased, the proportion of normal red. Iron particles staining: iron granulocytes accounted for 82%, coarse iron particles, but no annular mitochondria baby cells. Urine routine results are normal.