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实验动物系大白鼠,每组24只。将石棉水泥及水泥分别研成粉尘,分散度60～80%为5微米.分别将两种粉尘各50毫克加生理盐水1毫升注入实验动物气管内;对照组仅注入生理盐水1毫升。注入后3、9个月,对肺进行组织学与生化学研究。一、组织学:1.水泥尘组:噬尘细胞聚积于增厚的肺泡间隔、肺泡腔与血管旁;常见细的、或粗的胶原纤维积聚于邻近肺泡间隔处;肺泡间隔内无
Experimental animals, rats, 24 rats in each group. The asbestos cement and cement were ground into dust, dispersion degree of 60 to 80% to 5 microns respectively 50 mg of two kinds of dust plus saline 1 ml injected into the trachea of experimental animals; control group was injected only 1 ml of saline. Histological and biochemical studies of the lungs were performed 3 and 9 months after implantation. First, histology: 1. Cement dust group: the accumulation of dust cells in the thickened alveolar septa, alveolar cavity and blood vessels; common fine, or thick collagen fibers accumulate in the vicinity of the alveolar septa; within the alveolar septum