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细胞毒药物(cytotoxicdrugs,CD)系指在生物学方面具有危害性影响的药品。据美国医院药师协会(ASHP)对细胞毒药物的划定,主要特征如下[1]:(1)生殖系统毒性;(2)致癌性;(3)致畸胎或损伤生育;(4)低剂量(对实验动物或治疗病人)时致
Cytotoxic drugs (CDs) are those drugs that have a biological impact. According to the American Association of Hospital Pharmacists (ASHP) on the delineation of cytotoxic drugs, the main features are as follows [1]: (1) reproductive toxicity; (2) carcinogenicity; (3) teratogenic or injury fertility; Dose (for experimental animals or for treating patients)