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干细胞是一群具有自我更新和多向分化潜能的细胞群体,在特定的微环境下,可以分化成多种组织和器官,理论上一个干细胞可以发育成为完整的生物个体或组织器官。肿瘤干细胞理论在一定程度上解释了乳腺癌的形成,局部、远处转移及治疗抵抗等生物学行为。乳腺癌干细胞是当今科研领域的一个热点,有关乳腺癌干细胞理论及其在临床防治中的应用尚存在诸多问题。该文综述乳腺癌干细胞的研究进展。
Stem cells are a group of cells with self-renewal and multidirectional differentiation potential. Under certain microenvironment, stem cells can differentiate into many tissues and organs. In theory, a stem cell can develop into a complete biological individual or tissue organ. Cancer stem cell theory to a certain extent, explains the formation of breast cancer, local, distant metastasis and treatment of biological and biological behavior. Breast cancer stem cells are a hot topic in the field of scientific research. There are still many problems about breast cancer stem cell theory and its application in clinical prevention and treatment. This article reviews the research progress of breast cancer stem cells.