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目前,人们已越来越认识到胰腺干细胞的重要性。其中,对胰腺干细胞研究最多的是．用胰岛细胞移植治疗糖尿病,对于胰腺干细胞治疗各种胰腺损伤、胰腺炎、胰腺癌的研究仍在进行当中。对胰腺干细胞分子标志物的掌握是胰腺干细胞治疗研究的基础和重点,但目前缺乏唯一的干细胞标志物和可信的评价指标。此文将介绍干细胞、目前已知的胰腺干细胞分子标志物及其现状,如目前关注较多的PDX1、巢素蛋白、神经元素3、细胞角蛋白、波形蛋白、Notch信号及其他的分子标志物及其现状。
At present, people are more and more aware of the importance of pancreatic stem cells. Among them, the most studied of pancreatic stem cells is. With islet cell transplantation for the treatment of diabetes, pancreatic stem cells for the treatment of various pancreatic injuries, pancreatitis, pancreatic cancer research is still underway. The mastery of molecular markers of pancreatic stem cells is the basis of pancreatic stem cell therapy research and focus, but the only lack of stem cell markers and credible evaluation indicators. This article will introduce stem cells, the currently known molecular markers of pancreatic stem cells and their status quo, such as the current concern more PDX1, Nestin, Neuron 3, cytokeratin, vimentin, Notch signaling and other molecular markers And its status quo.