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采用ＳＤ大鼠以去氧胆酸钠作胰管逆行注射诱发急性出血坏死性胰腺炎，按Ｌ３（８）Z正交设计方法从整体到细胞以及分子水平观察茵陈蒿汤及其组分对急性胰腺炎的防治作用。结果表明：茵陈蒿汤及其组分能改善胰腺炎动物的一般状况，降低死亡率；减轻动物胰腺组织的病理改变；提高胰腺组织线粒体琥珀酸脱氢酶活性；提高胰腺组织。ｃＡＭＰ／ｃＧＭＰ比值。从而说明茵陈蒿汤及其组分对急性胰腺炎时的胰腺组织具有保护作用。
Acute rat hemorrhagic necrotizing pancreatitis was induced with sodium deoxycholate as a retrograde injection of sodium deoxycholate in SD rats. The arterial chrysanthemum soup and its components were observed from the whole to the cell and molecular level according to the L3(8)Z orthogonal design method. Prevention and treatment of acute pancreatitis. The results showed that: Yinchenhao Decoction and its components can improve the general condition of pancreatitis animal, reduce mortality; reduce the pathological changes of animal pancreatic tissue; increase the activity of succinate dehydrogenase of pancreatic tissue mitochondria; increase pancreatic tissue. cAMP/cGMP ratio. This shows that Yinchenhao Decoction and its components have protective effects on pancreatic tissue in acute pancreatitis.