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目的观察神经妥乐平对CHOP方案治疗非霍奇金淋巴瘤(NHL)所致周围神经系统疾病的疗效。方法采用CHOP化疗方案出现周围神经系统疾病的65例NHL患者随机分为A、B、C三组。A组15例,未治疗;B组25例,弥可保针剂0.5 mg,肌肉注射,1次/d,2周;C组25例,神经妥乐平针剂7.2 Nu,静脉滴注,1次/d,2周。结果治疗1周周围神经系统疾病好转率:B组20.0%,C组56.0% (P<0.01);治疗2周时其好转率分别为52.0%和84.0%(P<0.01);A组未见明显好转。结论神经妥乐平对CHOP化疗方案治疗NHL所致周围神经系统疾病有治疗作用。
Objective To observe the curative effect of neurotropin on CHOP-induced peripheral nervous system diseases caused by non-Hodgkin’s lymphoma (NHL). Methods A total of 65 NHL patients with peripheral neurological diseases treated with CHOP chemotherapy were randomly divided into A, B and C groups. A group of 15 cases, untreated; B group of 25 cases, the Mi can protect the needle 0.5 mg, intramuscular injection, 1 times / d, 2 weeks; C group 25 cases, neurotracer injection 7.2 Nu, intravenous drip, d, 2 weeks. Results The rate of improvement of peripheral nervous system diseases in one week after treatment was 20.0% in group B and 56.0% in group C (P <0.01), and the improvement rates were 52.0% and 84.0% respectively at 2 weeks (P0.01) Obvious improvement. Conclusion Neurotropin has a therapeutic effect on CHOP chemotherapy for the treatment of peripheral nervous system diseases caused by NHL.