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目的介绍尼莫地平在颅脑损伤中早期应用的重要意义。方法颅脑损伤患者38例随机分为甲乙两组,甲组不用尼莫地平,乙组24 h内用尼莫地平,比较两组患者的治疗时间和效果。结果早期应用尼莫地平与不用尼莫地平对部分脑功能疗效比较差异有统计学意义(P<0.05),CT扫描显示早期应用尼莫地平者与不用者脑水肿坏死病灶比较差异有统计学意义(P<0.01)。结论尼莫地平对颅脑损伤脑功能恢复有明显的疗效,而且用药愈早疗效愈显著。
Objective To introduce the importance of nimodipine in the early application of craniocerebral injury. Methods Thirty-eight patients with craniocerebral injury were randomly divided into two groups: A and B, nimodipine in group A, nimodipine in group B within 24 h, and the treatment time and effect of the two groups were compared. Results The early application of nimodipine and no nimodipine had a significant difference in the curative effect on some brain functions (P <0.05). CT scan showed that there were significant differences in the lesions of brain edema and necrosis between the nimodipine and non-users (P <0.01). Conclusion Nimodipine has a significant effect on the recovery of brain function after craniocerebral injury, and the earlier the effect is, the more obvious the effect is.