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目的观察医用透明质酸钠预防剖宫产术后组织粘连的效果。方法将株州市中心医院2008年3月-2015年3月行2次剖宫产的205例产妇随机分为对照组103例和观察组102例。对照组行第1次剖宫产术后常规关闭腹腔,观察组在手术部位及附近组织涂抹透明质酸钠,然后统计及比较两组产妇的盆腹腔粘连程度、粘连症状和并发症、再次手术时间及难度。结果观察组粘连发生程度及粘连发生率低于对照组,经比较差异有统计学意义(P<0.05)。观察组术后发热时间、肠鸣音恢复时间和肛门排气时间均短于对照组,经比较差异有统计学意义(P<0.05),其在术后3、6个月发生肠粘连的例数少于对照组,经比较差异有统计学意义(P<0.05)。观察组再次手术时间短于对照组,经比较差异有统计学意义(P<0.05)。结论应用透明质酸钠能有效治疗和预防剖宫产术后组织粘连,使孕产妇获益,值得应用推广。
Objective To observe the effect of medical sodium hyaluronate in preventing tissue adhesion after cesarean section. Methods 205 maternal women with 2 cesarean sections from March 2008 to March 2015 in Zhuzhou Central Hospital were randomly divided into control group (n = 103) and observation group (n = 102). In the control group, the abdominal cavity was closed routinely after the first cesarean section. The observation group was given sodium hyaluronate at the site of operation and nearby tissues. Then, the pelvic adhesions, adhesions symptoms and complications of the two groups were statistically analyzed and compared. Time and difficulty. Results The incidence of adhesions and the incidence of adhesions in the observation group were lower than those in the control group, and the difference was statistically significant (P <0.05). Postoperative fever, bowel sounds recovery time and anal exhaust time were shorter in the observation group than those in the control group (P <0.05), and the cases of intestinal adhesion occurred 3 and 6 months after operation The number of less than the control group, the difference was statistically significant (P <0.05). The observation group re-operation time is shorter than the control group, the difference was statistically significant (P <0.05). Conclusion The application of sodium hyaluronate can effectively treat and prevent tissue adhesion after cesarean section, so that pregnant women benefit, it is worth to promote the application.