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背景查格斯氏病是因感染克氏锥虫患病,是拉丁美洲地方病,导致800万~1 000万人感染,也是欧洲和美国主要的新传染病。传播途径包括先天携带、媒介物及通过未经筛查血液或器官捐赠传播。致命的并发症包括传导异常心肌病、心律失常、血栓性脑血管事件等。目的对澳大利亚第2例报告病例进行描述,为查格斯氏病的临床管理更新指南提供信息。讨论病程早期提供治疗可改善治疗效果。全科医生在感染者早期识别和转诊中起着重要作用。实际上,从感染到出现临床症状有几十年无症状潜伏期,因而为筛查及实施早期有效的干预提供了理想的背景。
Background Chagas disease is a congenital infection of Trypanosoma cruzi and is a endemic disease in Latin America that causes 8 million to 10 million infections and is also a major new infectious disease in Europe and the United States. The routes of transmission include innate carriage, transmission of the vector, and transmission through unscreened blood or organ donation. Mortal complications include conduction-induced cardiomyopathy, cardiac arrhythmias, and thrombotic cerebrovascular events. Objective To describe the second reported case in Australia and provide information on the updated guidelines on clinical management of Charlie’s disease. Discuss the course of the early treatment can improve the treatment effect. GPs play an important role in the early identification and referral of PLHIV. In fact, there are decades of asymptomatic latency from infection to presentation of clinical symptoms, thus providing an ideal context for screening and implementing early and effective interventions.