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目的观察特异性免疫治疗儿童哮喘的疗效。方法将 189例吸入性变应原皮试阳性的哮喘患儿分成两组 ,即对照组 5 2例 ,采用常规治疗法 ;治疗组 13 7例 ,在接受免疫治疗期间一般不用其他抗过敏药物 ,根据皮试阳性的变应原配制成单种或混合脱敏液进行脱敏治疗。结果治疗组显效 76例 (5 5 .47% ) ,有效 5 7例 (4 1.61% ) ,总有效率 97.0 8% ;对照组显效 4例 (7.69% ) ,有效 10例 (19.2 3 % ) ,总有效率 2 6.92 %。两组疗效有高度显著性差异 (P<0 .0 1)。结论特异性免疫治疗儿童哮喘是一种重要的、安全有效的治疗方法
Objective To observe the efficacy of specific immunotherapy in children with asthma. Methods A total of 189 asthmatic children with inhaled allergens skin test were divided into two groups: control group (n = 52) and conventional treatment group (n = 13). In the treatment group, no other anti-allergic drugs were generally used during the immunotherapy. Skin test-positive allergen formulated as a single or mixed desensitization solution for desensitization treatment. Results The effective rate of the treatment group was 76 cases (55.47%), the effective rate was 57 (4.61%), the total effective rate was 97.0%. The control group was markedly effective in 4 cases (7.69%), effective in 10 cases (19.23% The total effective rate of 2 6.92%. There was a highly significant difference between the two groups (P <0.01). Conclusion Specific immunotherapy of childhood asthma is an important, safe and effective treatment