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目的分析阿托伐他汀钙对老年冠心病合并慢性心力衰竭患者病死率的影响。方法选取我院近两年收治的老年冠心病合并慢性心力衰竭患者400例,按照到院就诊的先后顺序将这400例患者分为对照组和观察组,每组各200例,两组患者均给予相同的常规治疗,观察组患者在此基础上应用阿托伐他汀钙辅助治疗,治疗时常均为3个月,比较两组患者治疗前后的心功能指标以及随访期患者的病死率。结果治疗期间两组患者均未出现明显的药物不良反应。观察组患者的各项心功能指标明显优于对照患者,差异具有统计学意义(P<0.05);观察组患者的病死率明显低于对照组患者,差异具有统计学意义(P<0.05)。结论对老年冠心病合并慢性心力衰竭患者辅助应用阿托伐他汀钙治疗,对患者心功能的提高有明显的效果,可以有效降低患者的病死率。
Objective To analyze the effect of atorvastatin calcium on the mortality of elderly patients with coronary heart disease and chronic heart failure. Methods 400 cases of senile coronary heart disease complicated with chronic heart failure admitted to our hospital in recent two years were selected and divided into control group and observation group with 200 cases in each group according to the order of visiting hospital, Patients in the observation group were given atorvastatin calcium adjuvant therapy on the basis of the same routine treatment. The treatment group was usually 3 months. The cardiac function indexes before and after treatment and the case fatality rate of the patients in the follow-up period were compared. Results During the treatment, no obvious adverse drug reactions occurred in both groups. The cardiac function indexes of the observation group were significantly better than those of the control group, the difference was statistically significant (P <0.05). The mortality of the observation group was significantly lower than that of the control group (P <0.05). Conclusion Auxiliary atorvastatin calcium supplementation in elderly patients with CHD complicated with chronic heart failure has obvious effect on improving cardiac function and can effectively reduce the case fatality rate.