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目的观察依达拉奉联合神经节苷脂治疗急性脑梗死的临床效果及安全性。方法将182例急性脑梗死患者随机分为两组,治疗组采用依达拉奉和神经节苷脂分别加入生理盐水中静脉滴注,1次/d,21 d为1个疗程;对照组采用胞二磷胆碱注射液加入生理盐水中静脉滴注,疗程及用法同治疗组。结果治疗组基本治愈率为32.97%,总有效率为85.71%;明显高于对照组的18.68%、65.93%,两组比较差异有统计学意义(P<0.05)。结论早期应用依达拉奉和神经节苷脂治疗急性脑梗死,可加速神经功能的恢复,提高患者的生存质量,改善预后。
Objective To observe the clinical effect and safety of edaravone and ganglioside in the treatment of acute cerebral infarction. Methods A total of 182 patients with acute cerebral infarction were randomly divided into two groups. The treatment group was treated with edaravone and ganglioside by intravenous drip once a day for 21 days, while the control group was treated with Citicoline injection into the normal saline intravenous infusion, treatment and usage of the same treatment group. Results The cure rate of the treatment group was 32.97%, the total effective rate was 85.71%, which was significantly higher than that of the control group (18.68%, 65.93%). There was significant difference between the two groups (P <0.05). Conclusion The early application of edaravone and ganglioside in the treatment of acute cerebral infarction can accelerate the recovery of nerve function, improve the quality of life of patients and improve the prognosis.