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我院儿科1986～1987年对124例4月～3岁的婴幼儿腹泻患儿进行了654-2辅佐治疗。治疗方法是:在给予相应液体疗法的同时,重型患儿快速静脉推注654-2,每公斤1～1.5mg,必要时可重复2～3次;轻型患儿用654-2口服,每公斤0.5～1mg,每天3次。结果表明,654-2辅佐治疗组病情比液体治疗方法加抗生素治疗组的病程缩短2～3天。654-2能对抗婴幼儿腹泻时乙酰胆硷所致的胃肠道平滑肌痉挛,改善和活跃胃肠道的微循环,促进肠道功能恢复,减少肠粘膜渗出,有利于大便次数减少。654-2亦能改善肾脏微循环,使肾脏
From 1986 to 1987, 124 pediatric infantile diarrhea patients from April to 3 years old were treated with 654-2 adjuvant therapy in our pediatric department. Treatment is given: at the same time given the corresponding liquid therapy, rapid intravenous injection of heavy children 654-2, 1 ~ 1.5mg per kilogram, if necessary, repeat 2 to 3 times; 654-2 light children with oral, kg 0.5 ~ 1mg, 3 times a day. The results showed that 654-2 adjuvant treatment group than the liquid therapy plus antibiotic treatment course of disease shortened 2 to 3 days. 654-2 can antagonize infantile diarrhea, acetylcholine-induced gastrointestinal smooth muscle spasm, improve and active gastrointestinal microcirculation, promote intestinal function recovery, reduce leakage of intestinal mucosa, help to reduce the number of stool. 654-2 can also improve kidney microcirculation, so that the kidneys