论文部分内容阅读
Since only oral preparations of captopril are clinically available, intravenous captopril was studied in 10 patients with mild heart failure and in 20 severe. The results showed that intravenous captopril may rapidly reduce cardiac preload and afterload, increase cardiac output, inhibit reninangiotensin-aldosterone system, and depress plasma levels of catecholamine. After captopril infusion, a rapid symptomatie improvement occurred and the infusion could be well tolerated in patients with acute or severe heart failure. In addition, reversing hyponatremia and hypokalemia or improving azotcmia may benefit the patients with acute or severe heart failure.
Since only oral preparations of captopril are clinically available, intravenous captopril was studied in 10 patients with mild heart failure and in 20 severe. The results showed that intravenous captopril may rapidly reduce cardiac preload and afterload, increase cardiac output, inhibit renin angiotensin-aldosterone system, In addition, reversing hyponatremia and hypokalemia or improving azotcmia may benefit the patients with acute or severe heart failure.