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在中国 4城市儿童肺功能的队列研究数据基础上 ,通过 3步回归的统计方法 ,就空气污染和支气管炎或哮喘的交互作用对儿童肺功能的影响进行了研究。结果发现 ,空气颗粒物与支气管炎或哮喘等呼吸系统疾病对儿童肺功能有不利影响 ,而儿童在短期内患过支气管炎或哮喘会显著地加重空气颗粒物污染对 FVC和 FEV1 的有害影响 ,但从长期来看 ,这种有害影响趋于减弱。对于 FEV1/ FVC,支气管炎或哮喘与空气颗粒物对肺功能的作用是独立的。与气态污染物相比 ,颗粒物与呼吸系统疾病对儿童肺功能的交互作用更大
On the basis of cohort data of children’s lung function in 4 cities in China, the impact of air pollution and the interaction of bronchitis and asthma on lung function of children was studied by the statistical method of 3-step regression. The results showed that airborne particulates and respiratory diseases such as bronchitis or asthma had an adverse effect on children’s lung function, whereas children with bronchitis or asthma in the short term significantly increased the deleterious effects of airborne particulate contamination on FVC and FEV1, but from In the long run, this detrimental effect tends to weaken. For FEV1 / FVC, the effects of bronchitis or asthma and airborne particles on lung function are independent. Compared with gaseous pollutants, particulate matter and respiratory diseases have a greater interaction with children’s lung function