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动物和人的实验证明,单剂量静脉注射两性霉素B(AmB)几天乃至几周后可在尿中测得该药,且尿药浓度长期超过已报告的许多念珠菌种的MIC.因此,作者以静脉注射单剂量AmB治疗持续性念珠菌尿的病人.
Animal and human trials have shown that a single dose of amphotericin B (AmB) can be measured in urine within days or even weeks after administration of a single dose of amphotericin B and the urinary drug concentration has exceeded the MICs of many Candida species reported for a long time , The authors treated patients with persistent Candida albicans by a single intravenous injection of AmB.