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用蒿甲醚（Ａｒｔｅｍｅｔｈｅｒ）注射液在食蟹猴疟原虫———大劣按蚊动物模型中的试验结果显示：给感染猴一次性肌注６４ｍｇ／ｋｇ蒿甲醚后，９ｈ内原虫密度无明显变化，配子体数量仍在增加，与治疗前相比，吸血按蚊蚊胃内卵囊阳性率和蚊胃中卵囊数以及唾腺子孢子阳性率均明显降低。２３ｈ后，蚊胃未有卵囊形成；一次性给药达２５５ｍｇ／ｋｇ体重时，５ｈ后吸血按蚊蚊胃内未有卵囊形成。结果提示：蒿甲醚不仅具有快速杀灭疟原虫无性体，毒性低、用量少、在体内滞留时间长等特点，而且还具有抑制蚊胃内卵囊形成的作用。在一定量的药物作用情况下，可阻断疟原虫孢子增殖期的发育，而且时间快
Artemether (Artemether) injection in cynomolgus malaria - anopheles anopheles animal model test results showed that: a one-time intramuscular injection of infected monkeys artemether 6 4mg / kg after 9h protozoa The density of gametophyte was still increased with the number of gametocytes increasing. Compared with the pre-treatment, the positive rate of oocyst in mosquito and the number of oocysts in mosquito stomach and the positive rate of sporozoites in salivary glands were significantly decreased. After 23h, there was no oocyst formation in the mosquito stomach; when the dosage was 25.5mg / kg body weight once, oocysts were not formed in the stomach after 5h. The results suggest that artemether not only has the advantage of rapidly killing asexual malaria parasite, low toxicity, less dosage, long residence time in vivo, but also inhibits the formation of oocysts in the mosquito. In the case of a certain amount of drug action, can block the growth of the parasite’s sporulation period, and time is fast