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己酮可可碱(Pentoxifylline)是一种甲基黄磦呤衍生物,能增加肝组织表面氧张力、肝血流量及出血性休克复苏后生存率,也能减少炎症细胞素(cytoki-nes)引起的白细胞粘附和激活。本实验目的在于通过视频显微镜观察己酮可可碱对出血性休克复苏中小肠微血管的作用。作者将(Sprague-Dawley)雄鼠分成实验组(6只鼠)和对照组(5只鼠)。作双侧股静脉插管分别供复苏液和实验药品灌注用。左髂总动脉和右颈静脉插管分别作平均动脉压(MAP)测定和注射室温生理盐水指示剂用。一热敏电阻器由颈总动脉置于主动脉弓处以测定心排出量(CO)。剖腹取一段长2～3 cm 神经
Pentoxifylline is a methylxanthine derivative that increases oxygen tension on the surface of the liver tissue, hepatic blood flow, and survival after hemorrhagic shock resuscitation, as well as cytoki-nes-induced leukocyte depletion Adhesion and activation. The purpose of this experiment is to observe the effect of pentoxifylline on small intestinal microvascular in hemorrhagic shock resuscitation by video microscope. The male Sprague-Dawley rats were divided into experimental (6 mice) and control (5 mice) groups. For bilateral femoral vein catheter for resuscitation fluid and experimental drug infusion. Left common iliac artery and right jugular vein cannulation were measured mean arterial pressure (MAP) and injection of room temperature saline indicator. A thermistor is placed in the aortic arch by the common carotid artery to measure cardiac output (CO). Caesarean section to take a long 2 ~ 3 cm nerve