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[目的]对中西药联合五联疗法治疗慢性乙型肝炎的疗效进行探讨,为治疗慢性乙肝寻找更有效的药物和途径。[方法]将48例患者分成治疗组和对照组,治疗组患者采用中西药联合五联疗法,对照组患者给予a-干扰素,im。观测患者治疗前后的体征、症状、病毒复制指标、肝功能以及肝纤维化指标的变化情况。治疗3个月进行疗效判定。[结果]治疗组总有效率91.60%,对照组总有效率75.00%,治疗组临床疗效优于对照组(P<0.05)。[结论]采用中西药联合五联疗法治疗慢性乙肝对患者的体征、症状、抗干纤维化、抗病毒等的改善作用比a-干扰素强。
[Objective] To investigate the curative effect of combined traditional Chinese and western medicine in treating chronic hepatitis B and find more effective drugs and ways to treat chronic hepatitis B. [Methods] 48 patients were divided into treatment group and control group. The patients in the treatment group were treated with combination therapy of western medicine and western medicine and the control group were given interferon-α, im. Observed before and after treatment of patients with signs, symptoms, viral replication indicators, liver function and changes in liver fibrosis indicators. Treatment for 3 months to determine the efficacy. [Result] The total effective rate was 91.60% in the treatment group and 75.00% in the control group, and the clinical effect in the treatment group was better than that in the control group (P <0.05). [Conclusion] The improvement effect of chronic hepatitis B on signs, symptoms, anti-dry fibrosis, anti-virus and so on in patients with combined traditional Chinese and western medicine combined with five-factor therapy is stronger than a-interferon.