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目的:探讨血清前列腺特异性抗原筛查前列腺癌的价值。方法:采用化学发光免疫分析技术检测4 255名珠海市50岁以上男性的血清PSA含量,对PSA值>4.0μg/L的被检者进行穿刺活检或手术。结果:随着年龄增加,血清PSA浓度的增高,前列腺癌的发病率提高。通过血清PSA筛查,可以检出早期前列腺癌,占检出前列腺癌的94.4%。结论:应用血清PSA筛查前列腺癌可以早期、敏感发现可治愈的局限性的前列腺癌,临床意义重大。
Objective: To investigate the value of serum prostate specific antigen screening for prostate cancer. Methods: Chemiluminescence immunoassay was used to detect serum PSA levels in 4 255 men over the age of 50 in Zhuhai City, and biopsy or surgery on subjects with PSA> 4.0 μg / L. Results: With the increase of age, serum PSA concentration increased, the incidence of prostate cancer increased. Through the serum PSA screening, early prostate cancer can be detected, accounting for 94.4% of prostate cancer detected. CONCLUSIONS: Serum PSA screening for prostate cancer may lead to early detection of clinically significant localized prostate cancers with significant clinical implications.