Carbonic anhydrase enzymes Ⅱ, Ⅶ, Ⅸ and Ⅻ in colorectal carcinomas

• 作 者: Pia Viikilä Antti J Kivel
• 机 构: SchoolofMedicine,DepartmentofSurgery,DepartmentofBiochemistryandMolecularBiology,CentreofMolecularMe
• 出 处: 世界胃肠病学杂志：英文版
• 发表日期: 2016年36期
• 关键词: BIOMARKER Carbonic ANHYDRASE COLORECTAL cancer IMMUNOHISTOCHEMISTRY PROGNOSIS Su
• 基金项目: Supported by the Sigrid Jusélius Foundation,the Academy of Finland,the Medical Research Funds of Tampere University Hospital and Helsinki University Hospital,and Jane and Aatos Erkko Foundation

AIM To investigate expression of four alpha-carbonic anhydrases(CAs) in colorectal carcinomas(CRC) and compare the results with patients’ survival.METHODS Colorectal carcinoma samples from 539 CRC patients and control tissues were arranged as tissue micro