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1889年Anfimow and Blumenau首先报告1例颅内多发性脑膜瘤,1938年Cushing and Eisenhardt对多发性脑膜瘤的特点作了描述,指出多发性脑膜瘤就是在颅内同时或先后在不同部位生长一个以上的脑膜瘤。Levin等(1964)报告多发性脑膜瘤6例,并收集当时文献报导的共92例。此后又有Zervas等(1970)报告1例,Waga等(1972)报告4例,Lusins和Nakagawa(1981)报告15例均经CT扫描证实。Sheehy和Crockard(1983)报告手术后长期随诊者10例,京井等(1983)报告2例,O’lveil和Booth(1984)报告1例。鉴于国内目前尚未见到专题报告,今就近年来文献报告有关多发性脑膜瘤的定义、发病率、发病机理、治疗和预后等问题综述如下。
Anfimow and Blumenau first reported in 1889 an intracranial multiple meningioma, Cushing and Eisenhardt in 1938 described the characteristics of multiple meningiomas, that multiple meningiomas is in the brain at the same time or successively in different parts of the growth of more than one Meningioma. Levin et al (1964) reported multiple meningiomas in 6 cases, and collected a total of 92 cases reported in the literature. Since then Zervas et al. (1970) reported 1 case, Waga et al. (1972) reported 4 cases and Lusins and Nakagawa (1981) reported 15 cases confirmed by CT scan. Sheehy and Crockard (1983) reported long-term follow-up after operation in 10 cases, Jingjing et al. (1983) reported 2 cases and O’lveil and Booth (1984) reported 1 case. In view of the fact that no special reports have been reported in China at present, the recent reports on the definition, incidence, pathogenesis, treatment and prognosis of multiple meningiomas are summarized as follows.