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大动脉僵硬是血管老化的主要表现之一。本文对其机制、检测、影响因素及防治进行了综述。其中对该症有较大影响的高血压、动脉粥样硬化、高胆固醇血症和心性猝死等心血管疾病类因素,以及血管紧张素转换酶抑制剂、血管紧张索Ⅱ受体拮抗剂、利尿剂、非酶高级糖化终产物交联拮抗剂和血管活性肽酶抑制剂等可以降低本症的药物类防治措施给予了较详细的介绍。
Arterial stiffness is one of the major manifestations of vascular aging. This article reviews its mechanism, testing, influential factors and prevention and cure. Which have a greater impact on the disease of hypertension, atherosclerosis, hypercholesterolemia and sudden cardiac death and other cardiovascular disease factors, and angiotensin-converting enzyme inhibitors, angiotensin II receptor antagonists, diuresis Agents, non-advanced glycation end products of cross-linking antagonists and vasoactive peptidase inhibitors can reduce the symptoms of the drug class to give a more detailed prevention and control measures.