论文部分内容阅读
目的探讨尿碘含量对威海地区甲状腺结节患者发病的影响。方法从健康体检者中选取甲状腺结节患者共1390人,其中单发甲状腺结节651人,多发甲状腺结节739人,另外选取健康对照组(无甲状腺结节)1015人,记录其姓名、性别、身高、体重,尿碘含量,观察B超下甲状腺结节数量、大小、形态等。结果对照组、单发结节组与多发结节组之间尿碘中位数、身高、体重比较无统计学意义(P>0.05)。甲状腺结节组内尿碘≤50μg/L和≥300μg/L两组人数的构成比与对照组相比显著增加(P=0.004,P=0.01),尿碘100-199μg/L组时甲状腺结节组人数构成比下降,差别有统计学意义(P=0.001)。结论尿碘过高与过低均可导致甲状腺结节患病增加。
Objective To investigate the effect of urinary iodine on the incidence of thyroid nodules in Weihai area. Methods A total of 1390 patients with thyroid nodules were selected from healthy subjects, including 651 single thyroid nodules and 739 multiple thyroid nodules. In addition, 1015 healthy control subjects (without thyroid nodules) were selected and their names, sex , Height, weight, urinary iodine content, observe the number of thyroid nodules, size, shape and so on. Results There was no significant difference in median urinary iodine, height and weight between control group, single nodule group and multiple nodule group (P> 0.05). The proportion of urinary iodine ≤50μg / L and ≥300μg / L in thyroid nodule group was significantly higher than that in control group (P = 0.004, P = 0.01) The composition of the festival group decreased, the difference was statistically significant (P = 0.001). Conclusions Both high and low urinary iodine can lead to increased thyroid nodules.