论文部分内容阅读
轮状病毒感染所致的急性胃肠炎是一种世界性的常见病。由于本病主要影响婴幼儿,且秋冬季发病率最高,又称为秋季婴幼儿腹泻。常见临床症状为发热、呕吐和腹泻,大便呈水样,严重者发生脱水、休克甚至死亡。近年来的研究表明,轮状病毒性胃肠炎约占婴幼儿病毒性腹泻病例的50％。据Pollner等报告全世界每年死于轮状病毒性腹泻的婴幼儿500～1,800万。我国近年也有病例报告,庞其方等从秋季腹泻患儿大便滤液中发现轮状病毒与国外报道结果相似。现将国内外近几年的一些资料简述如下。病原学 1973年Bishop等在秋季腹泻患儿的十二指肠粘膜上皮细胞活体组织中发现了大量病毒颗粒。第二年,Kapikian用
Acute gastroenteritis caused by rotavirus infection is a worldwide common disease. As the disease mainly affects infants and young children, and the highest incidence in autumn and winter, also known as autumn infant diarrhea. Common clinical symptoms of fever, vomiting and diarrhea, stool was watery, severe dehydration occurred, shock and even death. In recent years, studies have shown that rotavirus gastroenteritis accounts for about 50% of infant cases of viral diarrhea. According to Pollner et al., About 500 to 18 million infants and young children die from rotavirus diarrhea each year in the world. In recent years, there are also reports of cases in our country. Pang Qi Fang et al. Found that rotavirus was found in stool filtrate of children with autumn diarrhea similar to those reported in foreign countries. Now some of the information at home and abroad in recent years are summarized below. Etiology In 1973, Bishop et al found that a large number of virus particles were found in the living tissues of duodenal mucosal epithelial cells in children with autumn diarrhea. The following year, Kapikian used