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硫磺软膏是临床上治疗疥疮的一种常用药。很多制剂手册均没介绍含量测定的方法,配制时硫磺分散不匀或形成团块,均影响疗效,制定有效的质量控制方法实属必要。我院参考福建晋江地区一院制剂手册的含量测定法,作了改进,取得良好效果,报道如下:文献介绍:精密称取检品0.1g,置锥形瓶中,加亚硫酸钠溶液(1:20)8 ml,附回流冷凝管,小火煮沸约1小时,至硫完全溶解,放冷过
Sulfur ointment is a commonly used drug for the clinical treatment of scabies. Many preparation manuals did not introduce the content determination method, the preparation of sulfur uneven distribution or formation of clumps, all affect the curative effect, to develop effective quality control methods is necessary. Reference to our hospital Fujian Jinjiang area a hospital manual preparation of content determination, made an improvement and achieved good results, reported as follows: References: Precision Weigh the seized goods 0.1g, set the conical flask, add sodium sulfite solution (1:20 ) 8 ml, with reflux condenser, boil for about 1 hour, to completely dissolve sulfur, let cool