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肌酸在体内主要以磷酸肌酸的形式存在，是肌肉及脑组织中能量的储存形式。选用昆明种小鼠经口给予肌酸 １５天，剂量分别为 １０ｇ ／ｋｇ 、３０ｇ ／ｋｇ 、６０ｇ ／ｋｇ 体重，另设阴性对照组。各剂量组小鼠负重游泳时间均比对照组延长，中、高剂量组小鼠游泳时间与对照组相比具极显著性差异（ Ｐ ＜ ００１）；各剂量组小鼠运动后血乳酸含量均低于对照组，低剂量组与对照组相比具显著性差异（ Ｐ ＜ ００１ ）；各剂量组小鼠血红蛋白含量均高于对照组，且具极显著性差异（ Ｐ ＜ ００１ ）。
Creatine in the body mainly in the form of creatine phosphate, muscle and brain tissue in the form of energy storage. Kunming mice were selected for oral administration of creatine 15 days, the dose was 1 0g / kg, 3 0g / kg, 6 0g / kg body weight, another set of negative control group. Compared with the control group, the swimming time of mice in each dose group was longer than that of the control group, while the swimming time of middle and high dose group was significantly different from that of the control group (P <001) (P <001). The hemoglobin content of mice in each dose group was higher than that of the control group (P <001), and there was a significant difference between the two groups 01).