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细胞外基质金属蛋白酶诱导因子 (EMMPRIN)广泛地存在于人类各种肿瘤细胞 ,刺激与肿瘤有关的成纤维细胞和肿瘤细胞自身的基质金属蛋白酶 (matrixmetalloproteinases,MMPs)合成增加 ,在恶性肿瘤的浸润和转移中起着重要的作用。现就其与恶性肿瘤之间的关系以及它的结构和功能作一综述
Extracellular matrix metalloproteinase inducer (EMMPRIN) is widely present in a variety of human tumor cells and stimulates the synthesis of tumor-associated fibroblasts and tumor cells themselves with increased matrix metalloproteinases (MMPs). In malignant tumor infiltration and Transfer plays an important role. Now its relationship with malignant tumors and its structure and function are reviewed