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目的:探讨腔腹内注入降纤酶和川穹嗪对结核性渗出性腹膜炎所致腹膜肥厚和粘连的影响。方法86例结核性渗出性腹膜炎患者随机分为注药组(46例)和对照组(40例),全身抗痨基础上注药组于每次抽液后注入降纤酶5U和川穹嗪注射液60ml。结果注药组有效35例(76.1%),对照组22例(55.0%)P<0.05。满6个月随访,注药组腹膜粘连包裹5例(10.9%),对照组13例(32.5%)P<0.05。结论腹膜腔内注入降纤酶和川穹嗪,有效降低腹膜肥厚粘连和包裹性积液发生。
Objective: To investigate the effect of intraperitoneal injection of defibrase and chrysogen on peritoneal hypertrophy and adhesions induced by tuberculous exudative peritonitis. Methods Totally 86 patients with tuberculous exudative peritonitis were randomly divided into injection group (n = 46) and control group (n = 40). On the basis of systemic anti-tuberculosis injection, 5U of defibrase and 5U Injection of 60ml of oxazine. Results The injection group was effective in 35 cases (76.1%), while the control group in 22 cases (55.0%) P <0.05. Over 6 months of follow-up, 5 cases (10.9%) were injected with peritoneal adhesions and 13 cases (32.5%) in the control group (P <0.05). Conclusion Intraperitoneal injection of defibrase and chrysin can effectively reduce the occurrence of peritoneal hypertrophy and parietal effusion.