Neuronal tolerance to hypoxia-ischemia through recombinant adeno-associated viral vectors expressing

• 作 者: Chunmei Chen Weizhong Yang Chu
• 机 构: DepartmentofNeurosurgery
• 出 处: 中国神经再生研究：英文版
• 发表日期: 2008年2期
• 关键词: 低氧血症 滤过性毒菌 临床分析 治疗方法 cerebral ischemia NOS apoptosis rAAV
• 基金项目: the Grant from Science and Technology Plan Program of Department of Education of Fujian Province. No. JAO4200

BACKGROUND: Studies have confirmed that neuronal nitric oxide synthase (nNOS) mediates neurotoxic effects during the early stages of hypoxia-ischemia,while inducible nitric oxide synthase (iNOS) mediates delayed neurotoxicity during advanced stages of hyp